In the area of nano photonics, scientists for the first time succeeded in integrating a laser with an organic gain medium on a silicon photonic chip. This approach is of enormous potential for low-cost biosensors that might be used for near-patient diagnosis once and without any sterilization expenditure similar to today’s strips for measuring blood sugar.
This is the first time organic lasers were integrated on a single silicon photonic chip, Christian Koos, researcher of KIT’s Institute of Photonics and Quantum Electronics (IPQ) and Institute of Microstructure Technology (IMT), reports. “The main advantage of the lasers consists in the fact that production of large series is associated with low costs. In the long term, manufacture at a price of some cents per laser might be feasible.”
Consumers are one step closer to benefiting from packaging that could give simple text warnings when food is contaminated with deadly pathogens like E. coli and Salmonella, and patients could soon receive real-time diagnoses of infections such as C. difficile right in their doctors’ offices, saving critical time and trips to the lab.
Researchers at McMaster University have developed a new way to print paper biosensors, simplifying the diagnosis of many bacterial and respiratory infections.
The new platform is the latest in a progression of paper-based screening technologies, which now enable users to generate a clear, simple answer in the form of letters and symbols that appear on the test paper to indicate the presence of infection or contamination in people, food or the environment.
“The simplicity of use makes the system easy and cheap to implement in the field or in the doctor’s office,” says John Brennan, director of McMaster’s Biointerfaces Institute, where the work was done with biochemist Yingfu Li and graduate student Carmen Carrasquilla.
“Imagine being able to clearly identify contaminated meat, vegetables or fruit. For patients suspected of having infectious diseases like C. diff, this technology allows doctors to quickly and simply diagnose their illnesses, saving time and expediting what could be life-saving treatments. This method can be extended to virtually any compound, be it a small molecule, bacterial cell or virus,” he says.
The research, in its formative stage, addresses a key problem facing current paper-based biosensing techniques which are labour-intensive, sometimes costly and inconvenient, and often difficult to mass produce.
Read more: Inkjet printer could produce simple tool to identify infectious disease, food contaminants