New drug delivery method targets cancer cells – not the entire body – and limits chemotherapy side effects
Now, researchers are developing a better delivery method by encapsulating the drugs in nanoballoons – which are tiny modified liposomes that, upon being struck by a red laser, pop open and deliver concentrated doses of medicine.
Because the nanoballoons encapsulate the anti-cancer drugs, they diminish the drugs’ interaction with healthy bodily systems.
“The nanoballoon is a submarine. The drug is the cargo. We use a laser to open the submarine door which releases the drug. We close the door by turning the laser off. We then retrieve the submarine as it circulates through the bloodstream.” Lovell will continue fundamental studies to better understand why the treatment works so well in destroying tumors in mice, and to optimize the process.