The University of Luxembourg today announced the publication of a research article in the internationally renowned scientific journal Nature Communications. The article is based on research on the interaction between microorganisms in the gut and the human body through the development of the artificial ‘HuMiX’ model.
HuMiX, ‘Human-Microbial X(cross)-talk’, represents an ‘organ-on-a-chip’ model for the human gastrointestinal tract. The model is developed to study the interaction between the microbiome, the community of all microbial organisms that live in and on our body, and the human host – all in vitro. The model and resulting insights will allow a better understanding of whether changes in the gut’s microbiome cause disease, or if such changes are a consequence of the disease.
The human microbiome is emerging as a key area of research within which HuMiX is the only model able to replicate the community of microorganisms in the gut while also allowing the study of their impact on human cell physiology. This technological breakthrough has not only the potential to change the way patients are given drugs by pre-screening their effects on patient-derived cells and microbiota outside of the body, but also open up a new market segment for HuMiX in clinical drug development.