The new system consists of a small, thin patch that is pressed against a patient’s arm during medical treatment and measures drugs in their bloodstream painlessly without drawing any blood. The tiny needle-like projection, less than half a milimetre long, resembles a hollow cone and doesn’t pierce the skin like a standard hypodermic needle.
“Many groups are researching microneedle technology for painless vaccines and drug delivery,” said researcher Sahan Ranamukhaarachchi, a PhD student and Vanier scholar in UBC’s faculties of applied science and pharmaceutical sciences, who developed this technology during a research exchange at PSI. “Using them to painlessly monitor drugs is a newer idea.”
Microneedles are designed to puncture the outer layer of skin, which acts as a protective shield, but not the next layers of epidermis and the dermis, which house nerves, blood vessels and active immune cells.
The Paul Scherrer Institute (PSI) is a multi-disciplinary research institute which belongs to the Swiss Federal Institutes of Technology Domain covering also the ETH Zurich and the EPFL.
It was established in 1988 by merging in 1960 established EIR (Eidgenössisches Institut für Reaktorforschung, Federal Institute for Reactor Research) and in 1968 established SIN (Schweizerisches Institut für Nuklearphysik, Swiss Institute for Nuclear Physics).
The PSI is a multi-disciplinary research centre for natural sciences and technology. In national and international collaboration with universities, other research institutes and industry, PSI is active in solid state physics, materials sciences, elementary particle physics, life sciences, nuclear and non-nuclear energy research, and energy-related ecology.
It is the largest Swiss national research institute with about 1,400 (year 2011) members of staff, and is the only one of its kind in Switzerland.
PSI is a User Laboratory and runs several particle accelerators. The 590MeV cyclotron, with its 72MeV companion pre-accelerator, is one of them. As of 2011, it delivers up to 2.2mA proton beam, which is the world record for such proton cyclotrons. It drives the spallation neutron source complex. The latest accelerator built (in 2001) is the Swiss Light Source (SLS), a synchrotron light source with a 2.4GeV electron storage ring. It is one of the world’s best with respect to electron beam brilliance and stability.
The Latest Updated Research News:
Paul Scherrer Institute research articles from Innovation Toronto
- Scientists develop painless and inexpensive microneedle system to monitor drugs Scientists develop painless and inexpensive microneedle system to monitor drugs – July 26, 2016
- Finding sustainable petrol – how solar energy can be transformed into fuel – July 9, 2016
- Rechargeable batteries that last 30 to 50 percent longer and re-charge more rapidly – July 4, 2016
- Tiny magnets mimic steam, water and ice – September 21, 2015
- Superconductivity switched on by magnetic field surprises scientists
- Germanium made compatible – faster communications on the way
- Pilot plant converts fruit and veggie waste into natural gas for cars
The sun is a clean and inexhaustible source of energy, with the potential to provide a sustainable answer to all future energy supply demands. There’s just one outstanding problem: the sun doesn’t always shine and its energy is hard to store. For the first time, researchers at the Paul Scherrer Institute PSI and the ETH Zurich have unveiled a chemical process that uses the sun’s thermal energy to convert carbon dioxide and water directly into high-energy fuels: a procedure developed on the basis of a new material combination of cerium oxide and rhodium. This discovery marks a significant step towards the chemical storage of solar energy.
The researchers published their findings in the research journal Energy and Environmental Science.
The sun’s energy is already being harnessed in various ways: whilst photovoltaic cells convert sun light into electricity, solar thermal installations use the vast thermal energy of the sun for purposes such as heating fluids to a high temperature. Solar thermal power plants involve the large-scale implementation of this second method: using thousands of mirrors, the sun light is focused on a boiler in which steam is produced either directly or via a heat exchanger at temperatures exceeding 500 °C. Turbines then convert thermal energy into electricity.
Researchers at the Paul Scherrer Institute PSI and the ETH Zurich have collaborated to develop a ground-breaking alternative to this approach. The new procedure uses the sun’s thermal energy to convert carbon dioxide and water directly into synthetic fuel.
Materials researchers at the Swiss Paul Scherrer Institute PSI in Villigen and the ETH Zurich have developed a very simple and cost-effective procedure for significantly enhancing the performance of conventional Li-ion rechargeable batteries. The procedure is scalable in size, so the use of rechargeable batteries will be optimized in all areas of application-whether in wristwatches, smartphones, laptops or cars. Battery storage capacity will be significantly extended, and charging times reduced.
The researchers reported on their results in the latest issue of the research journal Nature Energy.
It’s not necessary to re-invent the rechargeable battery in order to improve its performance. As Claire Villevieille, head of the battery materials research group at the Paul Scherrer Institute PSI says: “In the context of this competitive field, most researchers concentrate on the development of new materials.” In cooperation with colleagues at the ETH in Zurich, Villevieille and co-researcher Juliette Billaud took a different approach: “We checked existing components with a view to fully exploiting their potential.” Simply by optimizing the graphite anode – or negative electrode – on a conventional Li-ion battery, researchers were able to boost battery performance. “Under laboratory conditions, we were able to enhance storage capacity by a factor of up to 3. Owing to their complex construction, commercial batteries will not be able to fully replicate these results. But performance will definitely be enhanced, perhaps by as much as 30 – 50 percent: further experiments should yield more accurate prognoses.”
An international team of scientists constructs the first germanium-tin semiconductor laser for silicon chips
Scientists from Forschungszentrum Jülich and the Paul Scherrer Institute in Switzerland in cooperation with international partners have presented the first semiconductor consisting solely of elements of main group IV. As a consequence, the germanium-tin (GeSn) laser can be applied directly onto a silicon chip and thus creates a new basis for transmitting data on computer chips via light: this transfer is faster than is possible with copper wires and requires only a fraction of the energy. The results have been published in the journal Nature Photonics.
The transfer of data between multiple cores as well as between logic elements and memory cells is regarded as a bottleneck in the fast-developing computer technology. Data transmission via light could be the answer to the call for a faster and more energy efficient data flow on computer chips as well as between different board components. “Signal transmission via copper wires limits the development of larger and faster computers due to the thermal load and the limited bandwidth of copper wires. The clock signal alone synchronizing the circuits uses up to 30% of the energy – energy which can be saved through optical transmission,” explains Prof. Detlev Grützmacher, Director at Jülich’s Peter Grünberg Institute.
Some long-distance telecommunication networks and computing centres have been making use of optical connections for decades. They allow very high bandwidths even over long distances. Through optical fibres, signal propagation is almost lossless and possible across various wavelengths simultaneously: a speed advantage which increasingly benefits both micro- and nanoelectronics. “The integration of optical components is already well advanced in many areas. However, in spite of intensive research, a laser source that is compatible with the manufacturing of chips is not yet achievable,” according to the head of Semiconductor Nanoelectronics (PGI-9).