New drug delivery method targets cancer cells – not the entire body – and limits chemotherapy side effects
Now, researchers are developing a better delivery method by encapsulating the drugs in nanoballoons – which are tiny modified liposomes that, upon being struck by a red laser, pop open and deliver concentrated doses of medicine.
Because the nanoballoons encapsulate the anti-cancer drugs, they diminish the drugs’ interaction with healthy bodily systems.
“The nanoballoon is a submarine. The drug is the cargo. We use a laser to open the submarine door which releases the drug. We close the door by turning the laser off. We then retrieve the submarine as it circulates through the bloodstream.” Lovell will continue fundamental studies to better understand why the treatment works so well in destroying tumors in mice, and to optimize the process.
Roswell Park Cancer Institute (RPCI) is a cancer research and treatment center located in Buffalo, New York, USA.
Founded in 1898 by Dr. Roswell Park, RPCI is the nation’s first cancer center, and it is the only upstate New York facility to hold the National Cancer Institute designation of “comprehensive cancer center” and to serve as a member of the National Comprehensive Cancer Network. In addition, RPCI is the first dedicated medical facility for cancer treatment and research in the United States. The Institute is involved in drug development and conducts clinical research for cancer treatment.
The campus occupies 28 acres (110,000 m2) on the 100-acre Buffalo Niagara Medical Campus (BNMC) in downtown Buffalo, and includes 1,500,000 square feet (140,000 m2) of space equally distributed between clinical programs and research/education functions. A hospital building, completed in 1998, houses a diagnostic and treatment center. The campus includes a medical research complex and renovated existing education and research space. RPCI provides advanced treatment for all forms of adult and pediatric cancer, as well as cancer education and research facilities in 15 separate buildings that occupy approximately two million square feet.