New sensor for early detection of heart attack in humans, providing results in just 1 minute.
Heart disease is the leading cause of death for both men and women. Therefore, a fast and reliable diagnosis of heart attack is urgently needed.
A new study, led by Prof. Jaesung Jang (School of Mechanical and Nuclear Engineering) has developed an electrical immunosensor to detect the acute myocardial infarction, also known as a heart attack within a minute. The system works by measuring the level of cardiac troponin I (cTnI), a protein that is excreted by the heart muscle into the blood following a heart attack.
Prof. Jang states, “This new immunosensor is constructed in a different way than any other sensor.” He adds, “Owing to the new design of this immunosensor, this device is able to rapidly diagnose the level of heart attacks at the point of care.”
Using just a single droplet of blood, this immunosensor detects the target protein present in the blood serum following a heart attack and provides a result in 1 minute.
In the study, dielectrophoretic (DEP) forces have been applied to attract the target protein. The incubation time required for the detection is decreased through DEP-mediated biomarker concentration, in which the target protein is attracted onto the sensing areas via electrical forces. Therefore, the dielectrophoretic concentration of cTnI reduced the incubation time required from 60 min to 1 min.
Chang-Ho Han (School of Mechanical and Nuclear Engineering), a combined master’s-doctoral student in Prof. Jang’s group notes, “The level of cTnI within a single droplet of blood serum is not great.” He continues, “However, we were able to attract the target protein onto the sensing areas via electrical forces, thereby greatly improvingdetection time and detection limit.”
According to the research team, this novel immunosensor holds considerable potential for use as a platform for sensing distinct types of proteins, along with the feasibility of miniaturization and integration for biomedical diagnosis.
The findings of the research have been published in the August issue of the prestigious biotechnology journal Biosensors & Bioelectronics.
Inspiration from the natural world: Boosting flexible electronics
With increased study of bio-adhesives, a significant effort has been made in search for novel adhesives that will combine reversibility, repeated usage, stronger bonds and faster bonding time, non-toxic, and more importantly be effective in wet and other extreme conditions.
A team of Korean scientists?made up of scientists from Korea Institute of Science and Technology (KIST) and UNIST?has recently found a way to make building flexible pressure sensors easier—by mimicking the suction cups on octopus’s tentacles.
In their paper published in the current edition of Advanced Materials, the research team describes how they studied the structure and adhesive mechanism of octopus suckers and then used what they learned to develop a new type of suction based adhesive material.
According to the research team, “Although flexible pressure sensors might give future prosthetics and robots a better sense of touch, building them requires a lot of laborious transferring of nano- and microribbons of inorganic semiconductor materials onto polymer sheets.”
Ulsan National Institute of Science and Technology, simply referred to as UNIST (Hangul: 울산과학기술대학교; hanja: 울산과기대; MR: Ulsan Gwahak Gisul Daehakgyo), is the first independent national university established as a national research university in Ulsan, South Korea.
UNIST was founded in 2007 in response to growing demand for higher education in the Korean industrial capital of Ulsan, where world-renowned automotive (Hyundai Motor), shipbuilding (Hyundai Heavy Industries), petrochemical (SK Energy), and secondary cells industries are clustered. The vision of UNIST is to become a world-leading university to advance science and technology for the prosperity of humankind. With strong support from central and local governments, UNIST aims to rank in the top 10 of globally competitive universities emphasizing science and technology by the year 2030. The strategies for reaching this goal include creative, interdisciplinary and global education and research.
The Latest Updated Research News:
Ulsan National Institute of Science and Technology (UNIST) research articles from Innovation Toronto
- Octopus-Inspired Flexible Pressure Sensors – July 18, 2016
- Turning Human Waste into Next Generation Biofuel – June 1, 2016
- New Technique for Turning Sunlight into Hydrogen – February 17, 2016
- Printable Solid-State Lithium-Ion Batteries – August 15, 2015
- Electronic skin breakthrough makes it stretchy and transparent
- Breakthrough converts PET into non-toxic, biocompatible material to attack fungal infections
- Antibiotic Smart Bomb Can Target Specific Strains of Bacteria
- New technology can prevent cellular overload, dropped calls
- Fecal transplant pill knocks out recurrent C. diff infection, study shows
- Welcome to the Age of Denial
- Spaceflight alters bacterial social networks
- Is a common food fungus worsening the AIDS epidemic?
- Enhanced yet affordable material for supercapacitors
- Radically Different Sensor System Inspired by Bird Migration
- New Catalyst Replaces Platinum for Electric-Automobiles
- Battery Explosions a Thing of the Past
- New palm-sized microarray technique grows 1,200 individual cultures of microbes
- Korean researchers demonstrate a new class of transparent, stretchable electrodes
- China’s Twitter Revolution is Slow in Coming
- Assembly of nano-machines mimics human muscle
- HIV AIDS
- Handheld Probe Shows Great Promise for Oral Cancer Detection
- Self-Assembling Highly Conductive Plastic Nanofibers
- New Antibiotics?
- How Your Cat Is Making You Crazy
- How to Overhaul the Way Buildings Use Energy
- Osim’s new USB-powered US$170 uPixie uses EMS to massage and tone while you work
- China’s appetite for work and wealth
- New system could make censorship of Internet sites virtually impossible
- Geographic Analysis Offers New Insight Into Coral Disease Spread
- Governing by Design
- It’s All About Schools
- Patient reportedly cured of HIV infection after stem cell transplant
- Picture perfect
- How China’s Entrepreneurs Are Helping It Win
- Aren’t We Clever?
- The Achilles’ Heal of Aging
Researchers affiliated with Ulsan National Institute of Science and Technology (UNIST), South Korea, have found a new way to convert human waste into renewable energy sources.
A brand new outdoor laboratory has been recently launched at UNIST and this is expected to convert human waste into renewable energy sources, and possible to a monetary value.
Nestled in the center of UNIST campus, this hexagonal-shaped laboratory, called Science Walden Pavillion is now open to the public.
The pavillion, designed by Artist Seung-hyun Ko, Co-Founder of the Korean Nature Art Association (YATOO), consists of two floors with a total area of 122.25 square meter, featuring walls of translucent polycarbonate to allow visual connection between the inside and outside of the pavillion.