The University of New South Wales (UNSW) is an Australian public university.
Established in 1949, it is ranked among the top 60 universities in the world according to the QS World University Rankings. It has more than 50,000 students from over 120 countries.
The main UNSW campus is located on a 38 hectare site at Kensington, seven kilometres from the centre of Sydney. Other campuses are the College of Fine Arts in Paddington, [email protected], the University College at the Australian Defence Force Academy in Canberra, and sub-campuses at Randwick and Coogee in Sydney, as well as research stations around NSW.
UNSW is a founding member of the Group of Eight, a coalition of Australian research-intensive universities, and of the international network Universitas 21.
The Latest Updated Research News:
University of New South Wales (UNSW) research articles from Innovation Toronto
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UNSW medical scientists have discovered that DNA repair is compromised at important regions of our genome, shedding new light on the human body’s capacity to repair DNA damage.
Repairing damage in DNA from anything that causes a mutation, such as UV radiation and tobacco smoke, is a fundamental process that protects our cells from becoming cancerous.
In the study published today in the journal Nature, the scientists analysed more than 20 million DNA mutations from 1,161 tumours across 14 cancer types. They found that in many cancer types, especially skin cancers, the number of mutations was particular high in regions of the genome known as ‘gene promoters’. Significantly, these DNA sequences control how genes are expressed which in turn determine cell type and function.
The researchers showed that the numbers of DNA mutations are increased in gene promoters because the proteins that bind DNA to control gene expression block one of our cell repair systems responsible for fixing damaged DNA. This system is known as nucleotide excision repair (NER) and is one of a number of DNA repair mechanisms that occurs in human cells and the only one capable of repairing damage from UV light.